SCHEMBL30737491

SCHEMBL30737491

CC(=O)NCCOc1cccc(Oc2ccc(C(=O)O)c(N3C(=O)CCC3=O)n2)c1

nearest known ligand 0.53

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MTNR1A P48039 9/20 0.49
MTNR1B P49286 9/20 0.49
L3MBTL1 Q9Y468 1/20 0.42
USP2 O75604 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
MAPK1 P28482 1/20 0.41
HSD17B10 Q99714 1/20 0.41
KDM4E B2RXH2 2/20 0.40
LIPG Q9Y5X9 1/20 0.40
ALDH1A1 P00352 1/20 0.39
HPGD P15428 1/20 0.39
LMNA P02545 1/20 0.39
NR3C1 P04150 1/20 0.38
ACSS2 Q9NR19 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31724884 0.85 APEX1 (0.41) KDM4E
SCHEMBL31724657 0.80 HDAC3 (0.41) MTNR1AMTNR1BTSHR
SCHEMBL30737477 0.75 MTNR1A (0.48) MTNR1AMTNR1BL3MBTL1USP2ALOX15
SCHEMBL30737511 0.74 SORT1 (0.57)
SCHEMBL17164001 0.70 L3MBTL1 (0.75) MTNR1AMTNR1BL3MBTL1KDM4ELIPG
SCHEMBL885015 0.66 MTNR1A (1.00) MTNR1AMTNR1BL3MBTL1USP2ALOX15
Acetone SCHEMBL4249268 0.66 CA12 (0.36) L3MBTL1TSHRKDM4EALDH1A1HPGD
Acetone SCHEMBL20164099 0.65 CA12 (0.35) TSHRKDM4EALDH1A1HPGDLMNA
SCHEMBL16744389 0.65 MTNR1A (0.71) MTNR1AMTNR1BL3MBTL1USP2ALOX15
SCHEMBL3264491 0.65 MTNR1A (0.71) MTNR1AMTNR1BL3MBTL1USP2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed