Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | AURKA | O14965 | 1/20 | 0.51 |
| ▸ | KDR | P35968 | 1/20 | 0.51 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | SGK1 | O00141 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.48 |
| ▸ | GBA1 | P04062 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28271803 | 1.00 | HTR6 (0.62) | HTR6POLBALDH1A1AURKAKDR | |
| SCHEMBL28270291 | 0.89 | HTR6 (0.56) | HTR6POLBALDH1A1AURKAKDR | |
| SCHEMBL28271809 | 0.85 | HTR6 (0.55) | HTR6POLBKMT2AMEN1SGK1 | |
| SCHEMBL28270280 | 0.84 | HTR6 (0.61) | HTR6POLBKMT2AMEN1PKM | |
| SCHEMBL28270335 | 0.84 | HTR6 (0.66) | HTR6POLBKMT2AMEN1PKM | |
| SCHEMBL29530798 | 0.84 | HTR6 (0.61) | HTR6POLBKMT2AMEN1PKM | |
| SCHEMBL29118847 | 0.82 | ALDH1A1 (0.65) | POLBALDH1A1AURKAKDRAURKB | |
| SCHEMBL7163015 | 0.81 | ALDH1A1 (0.68) | POLBALDH1A1AURKAKDRAURKB | |
| SCHEMBL30737550 | 0.81 | HTR6 (0.62) | HTR6POLBKMT2AMEN1PKM | |
| SCHEMBL30737482 | 0.81 | MEN1 (0.65) | HTR6POLBALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510460-A | Benzo [ b ] thiophene derivative containing sulfonamide unit, and preparation method and application thereof | 贵州大学 | 2024-02-06 | — | — | CN | disclosed |