Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | HTR6 | P50406 | 2/20 | 0.62 |
| ▸ | SLC22A12 | Q96S37 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | BRD4 | O60885 | 2/20 | 0.50 |
| ▸ | SGK1 | O00141 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ITGA1 | P56199 | 1/20 | 0.48 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.47 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28271817 | 1.00 | MEN1 (0.65) | MEN1KMT2AHTR6SLC22A12POLB | |
| SCHEMBL28513321 | 0.89 | MEN1 (0.59) | MEN1KMT2AHTR6POLBPGR | |
| SCHEMBL9616781 | 0.87 | WDR5 (0.57) | MEN1KMT2AHTR6POLBBRD4 | |
| SCHEMBL28506242 | 0.85 | MEN1 (0.79) | MEN1KMT2AHTR6ALDH1A1 | |
| SCHEMBL28513733 | 0.85 | MEN1 (0.66) | MEN1KMT2AHTR6POLBALDH1A1 | |
| SCHEMBL28530757 | 0.84 | HTR6 (0.61) | MEN1KMT2AHTR6POLBALDH1A1 | |
| SCHEMBL28270335 | 0.84 | HTR6 (0.66) | MEN1KMT2AHTR6POLBPTPN2 | |
| SCHEMBL9616631 | 0.82 | WDR5 (0.67) | MEN1KMT2AHTR6POLBALDH1A1 | |
| SCHEMBL29118833 | 0.82 | PGR (0.65) | MEN1KMT2ASLC22A12PGRBRD4 | |
| SCHEMBL3769126 | 0.81 | PGR (0.73) | MEN1KMT2ASLC22A12PGRBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510460-A | Benzo [ b ] thiophene derivative containing sulfonamide unit, and preparation method and application thereof | 贵州大学 | 2024-02-06 | — | — | CN | disclosed |