Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 11/20 | 0.42 |
| ▸ | LIPG | Q9Y5X9 | 11/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | F11 | P03951 | 1/20 | 0.35 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | LAP3 | P28838 | 1/20 | 0.34 |
| ▸ | P4HB | P07237 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15810486 | 1.00 | LPL (0.42) | LPLLIPGCXCR2APOBEC3GF11 | |
| SCHEMBL22717876 | 0.86 | CXCR2 (0.42) | LPLLIPGCXCR2F11ANPEP | |
| SCHEMBL15000450 | 0.84 | PDCD1 (0.42) | LPLLIPGCXCR2F11PDCD1 | |
| SCHEMBL29712932 | 0.84 | PDCD1 (0.42) | LPLLIPGCXCR2F11PDCD1 | |
| SCHEMBL8269668 | 0.84 | JAK2 (0.35) | LPLLIPGCXCR2F11PDCD1 | |
| SCHEMBL13202078 | 0.83 | LPL (0.43) | LPLLIPGCXCR2ANPEPLAP3 | |
| SCHEMBL24299234 | 0.83 | CXCR2 (0.40) | LPLLIPGCXCR2F11ANPEP | |
| SCHEMBL30615277 | 0.83 | JAK2 (0.37) | LPLLIPGCXCR2F11PDCD1 | |
| SCHEMBL17951295 | 0.83 | JAK2 (0.37) | LPLLIPGCXCR2F11PDCD1 | |
| SCHEMBL15000451 | 0.83 | F11 (0.35) | LPLLIPGCXCR2F11PDCD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536642-A1 | HETEROCYCLIC COMPOUNDS AS PI3KA INHIBITORS | Synnovation Therapeutics, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023239846-A1 | HETEROCYCLIC COMPOUNDS AS PI3KΑ INHIBITORS | SYNNOVATION THERAPEUTICS, INC. (US) | 2023-12-14 | — | — | WO | disclosed |