Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.51 |
| ▸ | TNF | P01375 | 2/20 | 0.45 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | KCNQ3 | O43525 | 5/20 | 0.36 |
| ▸ | KCNQ2 | O43526 | 5/20 | 0.36 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.36 |
| ▸ | FADS1 | O60427 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | JAK2 | O60674 | 4/20 | 0.34 |
| ▸ | JAK1 | P23458 | 4/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 2/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26928464 | 1.00 | ASIC3 (0.51) | ASIC3TNFGRM4PIK3CAKCNQ3 | |
| Formic Acid SCHEMBL30738085 | 0.92 | ASIC3 (0.45) | ASIC3TNFGRM4PIK3CAKCNQ3 | |
| Formic Acid SCHEMBL26928765 | 0.92 | ASIC3 (0.45) | ASIC3TNFGRM4PIK3CAKCNQ3 | |
| SCHEMBL26928697 | 0.77 | FADS1 (0.60) | TNFGRM4PIK3CAKCNQ3KCNQ2 | |
| SCHEMBL30738032 | 0.77 | FADS1 (0.60) | TNFGRM4PIK3CAKCNQ3KCNQ2 | |
| SCHEMBL26928701 | 0.75 | GRM4 (0.47) | TNFGRM4PIK3CAKCNQ3KCNQ2 | |
| SCHEMBL26928896 | 0.73 | GRM4 (0.59) | TNFGRM4PIK3CA | |
| SCHEMBL26929269 | 0.73 | BACE1 (0.43) | TNFGRM4PIK3CAKCNQ3KCNQ2 | |
| SCHEMBL30824385 | 0.72 | TNF (0.51) | TNFGRM4PIK3CAKCNQ3KCNQ2 | |
| SCHEMBL30738201 | 0.72 | TNF (0.44) | TNFGRM4PIK3CAKCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536356-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | Xenon Pharmaceuticals Inc. (CA) | 2025-04-16 | — | — | EP | claimed |
| WO-2023239729-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | XENON PHARMACEUTICALS INC. (CA) | 2023-12-14 | — | — | WO | claimed |
| EP-4536356-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | Xenon Pharmaceuticals Inc. (CA) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023239729-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | XENON PHARMACEUTICALS INC. (CA) | 2023-12-14 | — | — | WO | disclosed |