Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.45 |
| ▸ | TNF | P01375 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.38 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.38 |
| ▸ | JAK2 | O60674 | 6/20 | 0.35 |
| ▸ | JAK1 | P23458 | 6/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 8/20 | 0.35 |
| ▸ | KCNQ2 | O43526 | 8/20 | 0.35 |
| ▸ | KCNQ1 | P51787 | 6/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 5/20 | 0.35 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL26928765 | 1.00 | ASIC3 (0.45) | ASIC3TNFPIK3CAGRM4JAK2 | |
| SCHEMBL30737893 | 0.92 | ASIC3 (0.51) | ASIC3TNFPIK3CAGRM4JAK2 | |
| SCHEMBL26928464 | 0.92 | ASIC3 (0.51) | ASIC3TNFPIK3CAGRM4JAK2 | |
| Formic Acid SCHEMBL30738123 | 0.80 | FADS1 (0.53) | TNFPIK3CAGRM4JAK2JAK1 | |
| Formic Acid SCHEMBL26928810 | 0.80 | FADS1 (0.53) | TNFPIK3CAGRM4JAK2JAK1 | |
| Formic Acid SCHEMBL27179281 | 0.78 | GRM4 (0.52) | TNFPIK3CAGRM4KCNQ3KCNQ2 | |
| Formic Acid SCHEMBL26928762 | 0.76 | KCNQ3 (0.42) | TNFPIK3CAGRM4KCNQ3KCNQ2 | |
| Formic Acid SCHEMBL26928748 | 0.75 | TNF (0.45) | TNFPIK3CAGRM4KCNQ3KCNQ2 | |
| Formic Acid SCHEMBL30738171 | 0.72 | CSNK2A2 (0.40) | TNFPIK3CAGRM4KCNQ3KCNQ2 | |
| Formic Acid SCHEMBL26928873 | 0.72 | CSNK2A2 (0.40) | TNFPIK3CAGRM4KCNQ3KCNQ2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536356-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | Xenon Pharmaceuticals Inc. (CA) | 2025-04-16 | — | — | EP | disclosed |
| US-20240101531-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | XENON PHARMACEUTICALS INC. (CA) | 2024-03-28 | — | — | US | disclosed |
| WO-2023239729-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | XENON PHARMACEUTICALS INC. (CA) | 2023-12-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240101531-A1 | PYRIDINAMINE DERIVATIVES AND THEIR USE AS POTASSIUM CHANNEL MODULATORS | KCNA1, KCNB1, KCNB2 | ASIC3 1055/4885TNF 4805/4885PIK3CA 1559/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.