SCHEMBL30738527

SCHEMBL30738527

COc1cnc(-c2nccnc2C(C)N2C(=O)c3ccccc3C2=O)cn1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 1/20 0.34
NPY1R P25929 1/20 0.34
NPY2R P49146 1/20 0.34
NPSR1 Q6W5P4 1/20 0.34
LMNA P02545 2/20 0.34
OXTR P30559 4/20 0.34
POLB P06746 2/20 0.33
ALDH1A1 P00352 2/20 0.33
ALOX15 P16050 1/20 0.33
TDP1 Q9NUW8 1/20 0.32
TSHR P16473 2/20 0.32
KDM4E B2RXH2 1/20 0.32
USP2 O75604 1/20 0.32
AVPR1A P37288 2/20 0.32
UGCG Q16739 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
MAOA P21397 1/20 0.32
AVPR2 P30518 1/20 0.31
PLAU P00749 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24728809 1.00 HPGD (0.34) HPGDNPY1RNPY2RNPSR1LMNA
SCHEMBL29775963 0.84 HPGD (0.41) HPGDNPY1RNPY2RNPSR1POLB
SCHEMBL23212678 0.84 HPGD (0.41) HPGDNPY1RNPY2RNPSR1POLB
SCHEMBL24728672 0.83 LMNA (0.35) LMNAALDH1A1ALOX15TDP1TSHR
SCHEMBL24728677 0.83 LMNA (0.38) LMNAALDH1A1ALOX15TDP1TSHR
SCHEMBL30069472 0.83 LMNA (0.35) LMNAALDH1A1ALOX15TDP1TSHR
SCHEMBL30738525 0.83 LMNA (0.38) LMNAALDH1A1ALOX15TDP1TSHR
SCHEMBL31087595 0.82 ALOX15 (0.41) LMNAALDH1A1ALOX15TDP1TSHR
SCHEMBL31087599 0.82 ALOX15 (0.41) LMNAALDH1A1ALOX15TDP1TSHR
SCHEMBL24729152 0.82 ALOX15 (0.41) LMNAALDH1A1ALOX15TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240287047-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS SYNGENTA CROP PROTECTION AG (CH) 2024-08-29 US disclosed
CN-117529477-A Pesticidally active diazine-amide compounds 先正达农作物保护股份公司 2024-02-06 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240287047-A1 PESTICIDALLY ACTIVE DIAZINE-AMIDE COMPOUNDS DDT, ACHE, NIT2 HPGD 2213/4885NPY1R 381/4885NPY2R 710/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.