SCHEMBL30738533

SCHEMBL30738533

CC(C)(C#N)c1ccc(C(F)(F)F)cc1C(N)=O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 2/20 0.49
KDM4E B2RXH2 2/20 0.40
ALDH1A1 P00352 2/20 0.40
HPGD P15428 2/20 0.40
HSD17B10 Q99714 2/20 0.40
CFTR P13569 1/20 0.39
CASP1 P29466 1/20 0.38
NOTUM Q6P988 1/20 0.37
PARP1 P09874 2/20 0.36
KMT2A Q03164 1/20 0.36
JAK2 O60674 1/20 0.36
MAP2K4 P45985 1/20 0.36
USP2 O75604 1/20 0.35
CYP2C19 P33261 1/20 0.35
RPS6KA3 P51812 1/20 0.35
JAK3 P52333 1/20 0.35
KIF11 P52732 1/20 0.35
TAS2R14 Q9NYV8 1/20 0.35
SYK P43405 1/20 0.35
MTOR P42345 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8608698 0.83 CES2 (0.56) CES2KDM4EALDH1A1HPGDHSD17B10
Methylamine SCHEMBL3227067 0.81 CES2 (0.68) CES2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL2856986 0.81 CES2 (0.72) CES2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL11298329 0.75 TAS2R14 (0.50) CES2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL7252332 0.75 CES2 (0.44) CES2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL4967948 0.74 ALDH1A1 (0.42) KDM4EALDH1A1HPGDHSD17B10PARP1
SCHEMBL2927261 0.74 CES2 (0.43) CES2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL12095449 0.73 CES2 (0.55) CES2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL5323409 0.73 CES2 (0.50) CES2KDM4EALDH1A1HPGDHSD17B10
SCHEMBL15775922 0.72 CES2 (0.42) CES2KDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117529477-A Pesticidally active diazine-amide compounds 先正达农作物保护股份公司 2024-02-06 CN disclosed