Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM2 | Q14416 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | KLK1 | P06870 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739109 | 0.88 | GRM2 (0.49) | GRM2LMNAALDH1A1KLKB1HSD17B10 | |
| SCHEMBL1909166 | 0.87 | GRM2 (0.53) | GRM2LMNAALDH1A1KLKB1HSD17B10 | |
| SCHEMBL30739042 | 0.86 | GRM2 (0.53) | GRM2LMNAALDH1A1KLKB1HSD17B10 | |
| SCHEMBL2821953 | 0.86 | LMNA (0.54) | GRM2LMNAALDH1A1KLKB1HSD17B10 | |
| SCHEMBL28595790 | 0.86 | ESR1 (0.55) | GRM2LMNAALDH1A1KLKB1HSD17B10 | |
| SCHEMBL3092869 | 0.85 | HSD17B10 (0.51) | GRM2LMNAALDH1A1KLKB1HSD17B10 | |
| SCHEMBL554548 | 0.85 | GRM2 (0.51) | GRM2LMNAALDH1A1KLKB1HSD17B10 | |
| SCHEMBL553801 | 0.85 | GRM2 (0.53) | GRM2LMNAALDH1A1KLKB1HSD17B10 | |
| SCHEMBL16246754 | 0.85 | KLKB1 (0.57) | GRM2LMNAALDH1A1KLKB1HSD17B10 | |
| SCHEMBL30739126 | 0.85 | HSD17B10 (0.55) | LMNAALDH1A1KLKB1HSD17B10KLK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561993-A1 | INHIBITORS OF PLASMA KALLIKREIN | Rezolute, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-120051460-A | Plasma kallikrein inhibitors | 瑞泽路特有限公司 | 2025-05-27 | — | — | CN | disclosed |
| WO-2024025907-A1 | INHIBITORS OF PLASMA KALLIKREIN | REZOLUTE, INC. (US) | 2024-02-01 | — | — | WO | disclosed |