SCHEMBL30739969

SCHEMBL30739969

C=C(F)c1cc(F)ccc1NC(=O)c1ccccc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 2/20 0.62
MAPT P10636 2/20 0.54
MEN1 O00255 5/20 0.53
KMT2A Q03164 5/20 0.53
KCNK2 O95069 1/20 0.52
NPC1 O15118 2/20 0.51
RAB9A P51151 2/20 0.51
HPGD P15428 1/20 0.51
TDP1 Q9NUW8 2/20 0.50
KCNK3 O14649 2/20 0.50
PKM P14618 2/20 0.50
POLB P06746 2/20 0.50
HDAC2 Q92769 1/20 0.50
KCNK9 Q9NPC2 1/20 0.50
LTC4S Q16873 1/20 0.50
GRIK1 P39086 1/20 0.50
CYP1A2 P05177 1/20 0.49
CYP2D6 P10635 1/20 0.49
TSHR P16473 1/20 0.49
CYP2C19 P33261 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30739633 0.81 RAB9A (0.59) HDAC1MAPTMEN1KMT2ANPC1
SCHEMBL30369924 0.80 HDAC1 (0.77) HDAC1MAPTMEN1KMT2ANPC1
SCHEMBL6588596 0.80 HDAC1 (0.77) HDAC1MAPTMEN1KMT2ANPC1
SCHEMBL23273772 0.78 HDAC1 (0.69) HDAC1MAPTMEN1KMT2ANPC1
Hydrochloric Acid SCHEMBL29693057 0.78 HDAC1 (0.74) HDAC1MAPTMEN1KMT2ANPC1
SCHEMBL30739823 0.78 HDAC1 (0.47) HDAC1MAPTMEN1KMT2ANPC1
SCHEMBL30739898 0.78 HDAC1 (0.64) HDAC1MAPTMEN1KMT2ANPC1
SCHEMBL15553332 0.77 HDAC1 (1.00) HDAC1MEN1KMT2AHDAC2
SCHEMBL29903248 0.77 HDAC1 (1.00) HDAC1MEN1KMT2AHDAC2
SCHEMBL28860211 0.77 KMT2A (0.68) HDAC1MAPTMEN1KMT2AKCNK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118044519-A Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-05-17 CN disclosed
CN-110072842-B Molecules having pesticidal utility, and intermediates, compositions and methods related thereto 科迪华农业科技有限责任公司 2024-02-02 CN disclosed