Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 6/20 | 0.40 |
| ▸ | REN | P00797 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 3/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | CTSB | P07858 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29877850 | 1.00 | FOLH1 (0.40) | FOLH1RENBACE1CTSLCTSB | |
| SCHEMBL31510082 | 0.95 | FOLH1 (0.43) | FOLH1CTSLCTSBCTSSCTSK | |
| SCHEMBL30565194 | 0.85 | NOD1 (0.40) | FOLH1CTSSCTSKNOD1 | |
| SCHEMBL31247951 | 0.84 | CAPN1 (0.44) | FOLH1CTSLCTSBCTSSCTSK | |
| SCHEMBL29714953 | 0.83 | FOLH1 (0.57) | FOLH1BACE1PTPN1CTSD | |
| SCHEMBL29714949 | 0.83 | FOLH1 (0.57) | FOLH1BACE1PTPN1CTSD | |
| SCHEMBL30277398 | 0.83 | FOLH1 (0.43) | FOLH1BACE1CTSLCTSBCTSS | |
| SCHEMBL31669627 | 0.83 | FOLH1 (0.40) | FOLH1RENCTSLCTSBCTSS | |
| SCHEMBL30524342 | 0.82 | GLO1 (0.42) | FOLH1RENCTSLCTSBCTSS | |
| SCHEMBL30831331 | 0.82 | CTSK (0.37) | RENCTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568669-A2 | CYTOTOXIC COMPOUNDS AND CONJUGATES THEREOF | Seagen Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-120018846-A | Cytotoxic compounds and conjugates thereof | 思进公司 | 2025-05-16 | — | — | CN | disclosed |
| WO-2024036329-A2 | CYTOTOXIC COMPOUNDS AND CONJUGATES THEREOF | SEAGEN INC. (US) | 2024-02-15 | — | — | WO | disclosed |
| EP-4321522-A1 | CYTOTOXIC COMPOUNDS AND CONJUGATES THEREOF | Seagen Inc. (US) | 2024-02-14 | — | — | EP | disclosed |