Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | TGFBR1 | P36897 | 7/20 | 0.36 |
| ▸ | TGFBR2 | P37173 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | ABCC3 | O15438 | 2/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 2/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 2/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 2/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22576664 | 1.00 | KDM4C (0.37) | KDM4CTGFBR1TGFBR2NPC1RAB9A | |
| SCHEMBL30460098 | 0.84 | TGFBR1 (0.36) | KDM4CTGFBR1TGFBR2NPC1RAB9A | |
| SCHEMBL30740368 | 0.83 | TGFBR1 (0.44) | KDM4CTGFBR1TGFBR2NPC1RAB9A | |
| SCHEMBL29067956 | 0.83 | SLCO1B1 (0.33) | KDM4CTGFBR1TGFBR2NPC1RAB9A | |
| SCHEMBL29922208 | 0.83 | SLCO1B1 (0.33) | KDM4CTGFBR1TGFBR2NPC1RAB9A | |
| SCHEMBL27157558 | 0.83 | SLCO1B1 (0.33) | KDM4CTGFBR1TGFBR2NPC1RAB9A | |
| SCHEMBL24982985 | 0.82 | SLCO1B1 (0.39) | KDM4CTGFBR1TGFBR2NPC1RAB9A | |
| SCHEMBL29411759 | 0.81 | SLCO1B1 (0.38) | KDM4CTGFBR1TGFBR2NPC1RAB9A | |
| SCHEMBL19715601 | 0.81 | SLCO1B1 (0.36) | KDM4CTGFBR1TGFBR2NPC1RAB9A | |
| SCHEMBL19715757 | 0.81 | SLCO1B1 (0.38) | KDM4CTGFBR1TGFBR2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024022314-A1 | TRIAZOLE COMPOUNDS AND USE THEREOF AS LPAR1 ANTAGONIST | 武汉人福创新药物研发中心有限公司 | 2024-02-01 | — | — | WO | disclosed |