Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.53 |
| ▸ | BCL9 | O00512 | 1/20 | 0.44 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | MGLL | Q99685 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21606732 | 0.80 | HTR2A (0.47) | HTR2AMGLLALDH1A1KMT2AMEN1 | |
| SCHEMBL7554208 | 0.80 | HTR2A (0.52) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL22257028 | 0.77 | HTR2A (0.51) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL7556049 | 0.75 | LMNA (0.62) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL5827968 | 0.75 | HTR2A (0.80) | HTR2ABCL9CTNNB1GAAALDH1A1 | |
| SCHEMBL31389409 | 0.75 | HTR2A (0.54) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL278663 | 0.73 | BCL9 (0.62) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL272963 | 0.73 | HTR2A (0.52) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL409598 | 0.73 | HTR2A (0.59) | HTR2ABCL9CTNNB1GAAMAPT | |
| SCHEMBL22230669 | 0.73 | HTR2A (0.47) | HTR2AGAAMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024022314-A1 | TRIAZOLE COMPOUNDS AND USE THEREOF AS LPAR1 ANTAGONIST | 武汉人福创新药物研发中心有限公司 | 2024-02-01 | — | — | WO | disclosed |
| CN-117447450-A | Triazole compounds and their use as LPAR1 antagonists | 武汉人福创新药物研发中心有限公司 | 2024-01-26 | — | — | CN | disclosed |