Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.62 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7561636 | 0.88 | MAPT (0.52) | LMNAHTR2AMAPTALDH1A1KMT2A | |
| SCHEMBL11755910 | 0.84 | LMNA (0.58) | LMNAMAPTALDH1A1KMT2AGAA | |
| SCHEMBL11637096 | 0.83 | LMNA (0.65) | LMNAMAPTALDH1A1KMT2ACYP2C19 | |
| SCHEMBL13313842 | 0.81 | LMNA (0.73) | LMNAMAPTALDH1A1KMT2ACYP2C19 | |
| SCHEMBL13313907 | 0.80 | HTR2A (0.42) | LMNAHTR2AMAPTALDH1A1KMT2A | |
| SCHEMBL7554208 | 0.79 | HTR2A (0.52) | HTR2AMAPTALDH1A1KMT2ABCL9 | |
| SCHEMBL11735334 | 0.79 | LMNA (0.77) | LMNAMAPTALDH1A1KMT2ACYP2C19 | |
| Ronidazole SCHEMBL635714 | 0.77 | LMNA (1.00) | LMNAMAPTALDH1A1KMT2ACYP2C19 | |
| SCHEMBL4873214 | 0.77 | LMNA (0.75) | LMNAMAPTALDH1A1KMT2ACYP2C19 | |
| SCHEMBL30740366 | 0.75 | HTR2A (0.53) | HTR2AMAPTALDH1A1KMT2ABCL9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1173414-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064864-A9 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RES CAMPAIGN TECH (GB) | 2001-12-27 | — | — | WO | disclosed |
| WO-2000064864-A1 | N-PROTECTED AMINES AND THEIR USE AS PRODRUGS | CANCER RESEARCH CAMPAIGN TECHNOLOGY LIMITED (GB) | 2000-11-02 | — | — | WO | disclosed |