Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 2/20 | 0.43 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.42 |
| ▸ | CPT1A | P50416 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745347 | 0.92 | KMT2A (0.43) | UCHL1USP30MEN1KMT2AALDH1A1 | |
| SCHEMBL29223963 | 0.83 | GPR119 (0.48) | UCHL1USP30MEN1KMT2AALDH1A1 | |
| SCHEMBL30740835 | 0.82 | MAPT (0.42) | UCHL1MEN1KMT2APOLBNR1H2 | |
| SCHEMBL29826469 | 0.81 | MEN1 (0.55) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL2807130 | 0.81 | MEN1 (0.55) | MEN1KMT2AALDH1A1POLBKDM4E | |
| SCHEMBL4541264 | 0.80 | L3MBTL1 (0.47) | UCHL1USP30MEN1KMT2AALDH1A1 | |
| SCHEMBL29039401 | 0.79 | CHRNB4 (0.47) | UCHL1USP30POLB | |
| SCHEMBL29410752 | 0.79 | CHRNB4 (0.47) | UCHL1USP30POLB | |
| SCHEMBL26999489 | 0.79 | CHRNB4 (0.47) | UCHL1USP30POLB | |
| SCHEMBL5156646 | 0.78 | USP30 (0.44) | UCHL1USP30MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |