Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | FKBP1A | P62942 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KLK7 | P49862 | 1/20 | 0.39 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | STS | P08842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745409 | 0.92 | NR1H2 (0.40) | MAPTNPSR1NR1H2NR1H3OPRK1 | |
| SCHEMBL29223963 | 0.84 | GPR119 (0.48) | KDM1AGPR119HSD11B1MEN1KMT2A | |
| SCHEMBL30740703 | 0.82 | UCHL1 (0.43) | MAPTNPSR1NR1H2NR1H3MEN1 | |
| SCHEMBL3257414 | 0.81 | GPR119 (0.56) | KDM1AGPR119MEN1KMT2ASTS | |
| SCHEMBL30740755 | 0.81 | LNPEP (0.38) | NPSR1OPRK1GPR119UCHL1 | |
| SCHEMBL18616623 | 0.80 | CHRNB4 (0.49) | MAPTNPSR1SIRT2KDM1AGPR119 | |
| SCHEMBL18616624 | 0.80 | CHRNB4 (0.49) | MAPTNPSR1SIRT2KDM1AGPR119 | |
| SCHEMBL18616633 | 0.79 | MAPT (0.47) | MAPTNPSR1FKBP1ANR1H2NR1H3 | |
| SCHEMBL30731233 | 0.78 | GPR119 (0.51) | GPR119HSD11B1KMT2AUCHL1 | |
| SCHEMBL30740852 | 0.77 | HSD11B1 (0.41) | MAPTNPSR1NR1H2NR1H3KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |