Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.46 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19040093 | 0.87 | HTR2A (0.53) | HTR2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL31000552 | 0.81 | ALDH1A1 (0.52) | HTR2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL30024944 | 0.79 | ALDH1A1 (0.57) | HTR2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL7870399 | 0.78 | SOS2 (0.68) | HTR2AHTR6MTNR1AMTNR1BSOS2 | |
| SCHEMBL31037788 | 0.76 | HDAC3 (0.56) | HTR2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8926562 | 0.74 | HTR2A (0.57) | HTR2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL17187807 | 0.74 | IDO1 (0.46) | HDAC4HDAC8ALDH1A1MEN1LMNA | |
| SCHEMBL10466658 | 0.74 | HDAC3 (0.46) | HTR2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8926558 | 0.73 | HTR2A (0.55) | HTR2AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL20673987 | 0.73 | KDM4E (0.56) | HTR2AHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |