Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.56 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31000552 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EHDAC3HDAC4 | |
| SCHEMBL31037788 | 0.82 | HDAC3 (0.56) | ALDH1A1HPGDKDM4EHDAC3HDAC4 | |
| SCHEMBL19040093 | 0.82 | HTR2A (0.53) | ALDH1A1HPGDKDM4EHDAC3HDAC4 | |
| SCHEMBL30740717 | 0.79 | HTR2A (0.54) | ALDH1A1HPGDKDM4EHDAC3HDAC4 | |
| SCHEMBL3566514 | 0.77 | ALDH1A1 (0.83) | ALDH1A1HPGDKDM4EHDAC3HDAC4 | |
| SCHEMBL5431939 | 0.77 | PTGS1 (0.52) | ALDH1A1HPGDKDM4EKMT2AMEN1 | |
| SCHEMBL1306655 | 0.76 | HDAC3 (0.80) | ALDH1A1HPGDKDM4EHDAC3HDAC4 | |
| SCHEMBL24328897 | 0.75 | MTNR1A (0.58) | ALDH1A1HPGDKDM4EHDAC3HDAC4 | |
| SCHEMBL260548 | 0.75 | DNA2 (0.56) | ALDH1A1GAAMAPTTSHRL3MBTL1 | |
| SCHEMBL24328928 | 0.75 | MTNR1A (0.58) | ALDH1A1HPGDKDM4EHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111303001-B | Synthesis method of indole mono-substituted 2-hydroxy-3- (1H-indol-3-yl) propionic acid compound | 苏州爱玛特生物科技有限公司 | 2022-12-20 | — | — | CN | disclosed |