Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR4 | O95977 | 3/20 | 0.53 |
| ▸ | MRGPRX4 | Q96LA9 | 11/20 | 0.48 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745406 | 0.83 | S1PR4 (0.59) | S1PR4MRGPRX4NPC1RAB9AHPGD | |
| SCHEMBL18783678 | 0.71 | MAPT (0.57) | MRGPRX4NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL14774697 | 0.70 | MAPK14 (0.46) | PKM | |
| SCHEMBL8618574 | 0.70 | MRGPRX4 (0.62) | MRGPRX4NPC1RAB9AHPGDSMN1; SMN2 | |
| SCHEMBL6958628 | 0.70 | SLC6A2 (0.66) | HPGDLMNA | |
| SCHEMBL11840387 | 0.69 | TDP1 (0.56) | S1PR4MRGPRX4HPGDSMN1; SMN2TSHR | |
| SCHEMBL27298983 | 0.69 | PDK2 (0.40) | S1PR4MRGPRX4NPC1RAB9AHPGD | |
| SCHEMBL30745344 | 0.69 | MRGPRX4 (0.45) | S1PR4MRGPRX4NPC1RAB9AHPGD | |
| SCHEMBL5466462 | 0.69 | ALDH1A1 (0.40) | NPC1RAB9ASMN1; SMN2TSHRTP53 | |
| SCHEMBL11711706 | 0.69 | MRGPRX4 (0.65) | MRGPRX4NPC1RAB9AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117043154-A | GPCR receptor agonists, pharmaceutical compositions comprising same, and methods of use thereof | 卡莫特医疗有限公司 | 2023-11-10 | — | — | CN | disclosed |