SCHEMBL30740904

SCHEMBL30740904

CN(CC(=O)O)C(=O)CC#N

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MVD P53602 1/20 0.40
MCL1 Q07820 4/20 0.37
DPP4 P27487 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
EYA2 O00167 1/20 0.32
APP P05067 1/20 0.32
ACE P12821 1/20 0.32
CASP1 P29466 1/20 0.32
PHF8 Q9UPP1 1/20 0.31
KDM2A Q9Y2K7 1/20 0.31
KDM4E B2RXH2 1/20 0.31
LMNA P02545 1/20 0.31
CHRM2 P08172 1/20 0.31
ADRA2A P08913 1/20 0.31
ALOX15 P16050 1/20 0.31
TSHR P16473 1/20 0.31
DRD1 P21728 1/20 0.31
SLC6A2 P23975 1/20 0.31
SLC6A4 P31645 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30740909 0.78 MCL1 (0.38) MCL1CASP1KDM4ETSHR
SCHEMBL1725614 0.77 MCL1 (0.39) MCL1TDP1EYA2APPACE
SCHEMBL9653268 0.77
SCHEMBL10629781 0.76 CA12 (0.55) MCL1TDP1CASP1KDM4ELMNA
SCHEMBL3263776 0.76
SCHEMBL14417883 0.76 MCL1 (0.38) MCL1DPP4CASP1KDM4E
SCHEMBL14673211 0.74 MCL1 (0.37) MCL1DPP4CASP1CHRM2
SCHEMBL1900516 0.74 MCL1 (0.37) MCL1DPP4CASP1
SCHEMBL333490 0.74
SCHEMBL23986755 0.72 MVD (0.44) MVDTDP1EYA2APPACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed
EP-4561975-A1 FTO INHIBITORS RPXDS Co., Ltd (CN) 2025-06-04 EP disclosed
WO-2024022491-A1 FTO INHIBITORS RPXDS CO., LTD (CN) 2024-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 MVD 3468/4885MCL1 3268/4885DPP4 1363/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.