SCHEMBL30740916

SCHEMBL30740916

CCNCCCc1ccccc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.56
CHRM2 P08172 1/20 0.55
CASR P41180 2/20 0.45
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 1/20 0.44
AOC3 Q16853 1/20 0.44
SIGMAR1 Q99720 2/20 0.44
HTR1A P08908 1/20 0.44
ADRA2B P18089 1/20 0.44
ADRA2C P18825 1/20 0.44
HRH2 P25021 1/20 0.44
HTR2A P28223 1/20 0.44
HTR2C P28335 1/20 0.44
HRH1 P35367 1/20 0.44
OPRM1 P35372 1/20 0.44
DRD3 P35462 1/20 0.44
OPRK1 P41145 1/20 0.44
HTR2B P41595 1/20 0.44
HTR5A P47898 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13911221 0.89 TAAR1 (0.66) TAAR1CHRM2SLC6A2SLC6A4SLC6A3
SCHEMBL11397793 0.81 TAAR1 (0.78) TAAR1CHRM2CASRSLC6A2SLC6A4
SCHEMBL10880242 0.80 CHRM2 (0.58) TAAR1CHRM2SLC6A4SIGMAR1MPO
SCHEMBL18977430 0.79 CHRM2 (0.55) TAAR1CHRM2SLC6A4SIGMAR1HTR2A
SCHEMBL256701 0.78 TAAR1 (0.56) TAAR1CHRM2SLC6A2SLC6A4SLC6A3
SCHEMBL91132 0.78 TAAR1 (0.60) TAAR1SLC6A2SLC6A4SLC6A3AOC3
SCHEMBL5071552 0.76 CHRM2 (0.53) TAAR1CHRM2CASRSLC6A2SLC6A4
SCHEMBL2471147 0.76 CHRM2 (0.62) TAAR1CHRM2LMNAPNMTIDO1
SCHEMBL1374203 0.76 LIPG (0.55) TAAR1CHRM2SLC6A2SLC6A4SLC6A3
Ammonia Solution, Strong SCHEMBL9427687 0.76 TAAR1 (0.54) TAAR1CHRM2SLC6A2SLC6A4SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed
EP-4561975-A1 FTO INHIBITORS RPXDS Co., Ltd (CN) 2025-06-04 EP disclosed
CN-119546566-A FTO inhibitors 瑞璞鑫(苏州)生物科技有限公司 2025-02-28 CN disclosed
WO-2024022491-A1 FTO INHIBITORS RPXDS CO., LTD (CN) 2024-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 TAAR1 228/4885CHRM2 1187/4885CASR 1809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.