SCHEMBL30740928

SCHEMBL30740928

CNCc1cc(C)c(F)cc1F

nearest known ligand 0.43

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 17/20 0.43
HTR2A P28223 14/20 0.43
KCNH2 Q12809 10/20 0.43
MCL1 Q07820 1/20 0.35
SLC6A2 P23975 3/20 0.35
HTR2C P28335 3/20 0.33
SLC6A3 Q01959 2/20 0.33
CHRM4 P08173 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8337555 0.84 DPP4 (0.42) SLC6A4HTR2AKCNH2MCL1SLC6A2
SCHEMBL14036682 0.82 SLC6A4 (0.37) SLC6A4HTR2AKCNH2MCL1SLC6A2
SCHEMBL8229041 0.77 SLC6A4 (0.50) SLC6A4HTR2AKCNH2SLC6A2SLC6A3
Hydrochloric Acid SCHEMBL30475257 0.75 SLC6A4 (0.49) SLC6A4HTR2AKCNH2MCL1SLC6A2
Hydrochloric Acid SCHEMBL29200951 0.75 SLC6A4 (0.49) SLC6A4HTR2AKCNH2MCL1SLC6A2
SCHEMBL18827218 0.75 DPP4 (0.33)
SCHEMBL12800814 0.75 NOS3 (0.34) MCL1
SCHEMBL12923079 0.73 DPP4 (0.32)
SCHEMBL19433173 0.73 DPP4 (0.36) HTR2AHTR2C
SCHEMBL19868426 0.73 DPP4 (0.32) SLC6A4SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260035341-A1 FTO INHIBITORS RPXDS CO LTD (CN) 2026-02-05 US disclosed
EP-4561975-A1 FTO INHIBITORS RPXDS Co., Ltd (CN) 2025-06-04 EP disclosed
CN-119546566-A FTO inhibitors 瑞璞鑫(苏州)生物科技有限公司 2025-02-28 CN disclosed
WO-2024022491-A1 FTO INHIBITORS RPXDS CO., LTD (CN) 2024-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260035341-A1 FTO INHIBITORS FTO, LDLR, GPR119 SLC6A4 1011/4885HTR2A 813/4885KCNH2 2351/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.