Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 3/20 | 0.42 |
| ▸ | JAK3 | P52333 | 3/20 | 0.42 |
| ▸ | EIF4E | P06730 | 2/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740948 | 0.90 | EIF4E (0.44) | JAK2JAK3EIF4EMAPTALDH1A1 | |
| SCHEMBL30741014 | 0.88 | EIF4E (0.45) | JAK2JAK3EIF4EMAPTALDH1A1 | |
| SCHEMBL30741069 | 0.83 | KDM4E (0.41) | JAK2JAK3EIF4EMAPTALDH1A1 | |
| SCHEMBL30741043 | 0.81 | KDM4E (0.47) | JAK2JAK3EIF4EMAPTALDH1A1 | |
| SCHEMBL30740973 | 0.81 | AR (0.48) | MAPTALDH1A1GAASMN1; SMN2RAB9A | |
| SCHEMBL30741000 | 0.78 | JAK2 (0.47) | JAK2JAK3MAPTALDH1A1GAA | |
| SCHEMBL29158667 | 0.76 | NPC1 (0.46) | EIF4EDHODHMAPTALDH1A1GAA | |
| SCHEMBL276916 | 0.74 | ALDH1A1 (0.44) | JAK2JAK3MAPTALDH1A1GAA | |
| SCHEMBL276058 | 0.74 | MAPT (0.47) | JAK2JAK3MAPTALDH1A1GAA | |
| SCHEMBL30741118 | 0.72 | KDM4E (0.42) | JAK2JAK3DHODHMAPTPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |