Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30740940 | 0.90 | JAK2 (0.42) | EIF4EHRH2HRH1GAAMAPT | |
| SCHEMBL30741069 | 0.90 | KDM4E (0.41) | EIF4EHRH2HRH1GAAMAPT | |
| SCHEMBL30740973 | 0.87 | AR (0.48) | GAAMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL30741043 | 0.83 | KDM4E (0.47) | EIF4EGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30741014 | 0.83 | EIF4E (0.45) | EIF4EGAAMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL30741118 | 0.78 | KDM4E (0.42) | MAPTPDK2KDM4EJAK2JAK3 | |
| SCHEMBL276058 | 0.76 | MAPT (0.47) | GAAMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL276916 | 0.76 | ALDH1A1 (0.44) | GAAMAPTALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL29158750 | 0.75 | EIF4E (0.49) | EIF4EHRH2HRH1GAAMAPT | |
| SCHEMBL30741012 | 0.74 | KDM4E (0.52) | MAPTPDK2KDM4EJAK2JAK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |