Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | EIF4E | P06730 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | CACNA1D | Q01668 | 2/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | HRH2 | P25021 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | CRHBP | P24387 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30741014 | 0.90 | EIF4E (0.45) | KDM4EEIF4EMAPTALDH1A1GAA | |
| SCHEMBL30740948 | 0.90 | EIF4E (0.44) | KDM4EEIF4EMAPTALDH1A1GAA | |
| SCHEMBL30740973 | 0.88 | AR (0.48) | MAPTALDH1A1GAASMN1; SMN2LMNA | |
| SCHEMBL30741043 | 0.86 | KDM4E (0.47) | KDM4EEIF4EMAPTALDH1A1GAA | |
| SCHEMBL30741012 | 0.85 | KDM4E (0.52) | KDM4EMAPTPDK2MEN1HSP90AA1 | |
| SCHEMBL30741020 | 0.84 | AR (0.51) | KDM4EMAPTALDH1A1GAASMN1; SMN2 | |
| SCHEMBL30740940 | 0.83 | JAK2 (0.42) | KDM4EEIF4EMAPTALDH1A1GAA | |
| SCHEMBL30741061 | 0.83 | L3MBTL1 (0.44) | KDM4EMAPTALDH1A1PDK2MEN1 | |
| SCHEMBL30741118 | 0.82 | KDM4E (0.42) | KDM4EMAPTPDK2MEN1HSP90AA1 | |
| SCHEMBL30741051 | 0.82 | KDM4E (0.43) | KDM4EMAPTALDH1A1SMN1; SMN2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |