SCHEMBL30740971

SCHEMBL30740971

CCOC(=O)c1c[nH]c(-c2ccc(C(F)(F)F)cc2)c1-c1ccc(OC)c(OC)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.49
TUBB P07437 1/20 0.49
TUBA3C P0DPH7 1/20 0.49
TUBA1B P68363 1/20 0.49
TUBA4A P68366 1/20 0.49
TUBB4B P68371 1/20 0.49
TUBB3 Q13509 1/20 0.49
TUBB2A Q13885 1/20 0.49
TUBB8 Q3ZCM7 1/20 0.49
TUBA3E Q6PEY2 1/20 0.49
TUBA1A Q71U36 1/20 0.49
TUBA1C Q9BQE3 1/20 0.49
TUBB6 Q9BUF5 1/20 0.49
TUBB2B Q9BVA1 1/20 0.49
TUBB1 Q9H4B7 1/20 0.49
HTT P42858 1/20 0.43
KDM4E B2RXH2 2/20 0.41
MRGPRX4 Q96LA9 1/20 0.41
MAPT P10636 6/20 0.41
LMNA P02545 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30741086 0.86 KDM4E (0.43) HTTKDM4EMRGPRX4MAPTHPGD
SCHEMBL30741107 0.86 JAK2 (0.48) HTTKDM4EMAPTHPGDALDH1A1
SCHEMBL30741053 0.86 JAK2 (0.47) HTTKDM4EMRGPRX4MAPTHPGD
SCHEMBL30740997 0.85 KDM4E (0.48) HTTKDM4EMRGPRX4MAPTHPGD
SCHEMBL30741061 0.84 L3MBTL1 (0.44) KDM4EMAPTALDH1A1MEN1KMT2A
SCHEMBL30740963 0.84 MAPT (0.44) MAPTLMNA
SCHEMBL30741035 0.84 GCGR (0.49) KDM4EMAPTMEN1KMT2ANPC1
SCHEMBL30741092 0.83 JAK2 (0.48) KDM4EMAPTLMNAALDH1A1GAA
SCHEMBL30741023 0.82 KDM4E (0.45) KDM4EMRGPRX4MAPTHPGDALDH1A1
SCHEMBL30740955 0.82 MAPT (0.44) KDM4EMAPTHPGDALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117396465-A Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same 阿斯克里斯有限公司 2024-01-12 CN disclosed