Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK2 | O60674 | 1/20 | 0.52 |
| ▸ | JAK3 | P52333 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | GAA | P10253 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156503 | 0.85 | SMN1; SMN2 (0.54) | KMT2AMEN1KDM4EGAAMAPT | |
| SCHEMBL1156007 | 0.81 | L3MBTL1 (0.52) | JAK2JAK3KMT2AMEN1KDM4E | |
| SCHEMBL7179755 | 0.81 | PLAU (0.53) | SLC6A2SLC6A4SLC6A3HPGD | |
| SCHEMBL7452434 | 0.80 | MEN1 (0.55) | JAK2JAK3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL30741111 | 0.80 | HDAC3 (0.41) | KDM4EMAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL1156651 | 0.80 | GCGR (0.53) | KMT2AMEN1KDM4EMAPTSMN1; SMN2 | |
| SCHEMBL29552309 | 0.80 | ALPL (0.51) | MAPTSMN1; SMN2RAB9ALMNANPC1 | |
| SCHEMBL30741062 | 0.79 | JAK2 (0.52) | JAK2JAK3MAPTALDH1A1HPGD | |
| SCHEMBL30741072 | 0.79 | JAK2 (0.52) | JAK2JAK3KMT2AMEN1KDM4E | |
| SCHEMBL30741041 | 0.78 | POLB (0.46) | SMN1; SMN2LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |