Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | GCGR | P47871 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA7 | P43166 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156651 | 0.86 | GCGR (0.53) | GCGRMAPK14NPC1KDM4EMAPT | |
| SCHEMBL29552309 | 0.83 | ALPL (0.51) | GCGRNPC1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30741072 | 0.83 | JAK2 (0.52) | NPC1KDM4EMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30740939 | 0.82 | CA12 (0.42) | GCGRMAPK14CA12CA1CA2 | |
| SCHEMBL1156503 | 0.80 | SMN1; SMN2 (0.54) | NPC1KDM4EMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30740988 | 0.80 | JAK2 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29551706 | 0.80 | MAPT (0.47) | GCGRMAPK14KDM4EMAPTIMPDH2 | |
| SCHEMBL30741062 | 0.80 | JAK2 (0.52) | MAPTCYP1A2 | |
| SCHEMBL1156007 | 0.80 | L3MBTL1 (0.52) | NPC1KDM4EMAPTRAB9ASMN1; SMN2 | |
| SCHEMBL1278441 | 0.80 | CA12 (0.41) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396465-A | Novel oxazole derivative for preventing or treating allergic diseases and pharmaceutical composition containing the same | 阿斯克里斯有限公司 | 2024-01-12 | — | — | CN | disclosed |