Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.32 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.32 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | KDM1A | O60341 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30741098 | 0.84 | PSEN1 (0.39) | HRH3SMN1; SMN2KDM1AMAPTDDB1 | |
| SCHEMBL30741063 | 0.84 | DPP4 (0.39) | HRH3DPP4KDM1A | |
| SCHEMBL30968408 | 0.82 | HRH3 (0.33) | HRH3DPP4SMN1; SMN2DDB1CRBN | |
| SCHEMBL30968553 | 0.81 | ACHE (0.33) | DPP4KDM1AKDM4EMAPTDDB1 | |
| SCHEMBL30968556 | 0.79 | DPP4 (0.32) | DPP4KDM1A | |
| SCHEMBL30968539 | 0.78 | HTR2A (0.32) | HRH3 | |
| SCHEMBL31634911 | 0.78 | RORC (0.41) | USP30 | |
| SCHEMBL30968407 | 0.76 | GPR119 (0.31) | — | |
| SCHEMBL30968422 | 0.75 | — | — | |
| SCHEMBL30968464 | 0.74 | BRD3 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112823037-B | Inhibition of deubiquitinase USP25 and USP28 | 瓦洛健康股份有限公司 | 2023-12-19 | — | — | CN | disclosed |