Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | UCHL1 | P09936 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30064881 | 0.94 | KLK7 (0.38) | KLK7MEN1KMT2ANPC1KLK5 | |
| SCHEMBL6052900 | 0.94 | KLK7 (0.38) | KLK7MEN1KMT2ANPC1KLK5 | |
| SCHEMBL6052905 | 0.94 | KLK7 (0.38) | KLK7MEN1KMT2ANPC1KLK5 | |
| SCHEMBL27043967 | 0.94 | KLK7 (0.38) | KLK7MEN1KMT2ANPC1KLK5 | |
| SCHEMBL4378972 | 0.94 | KLK7 (0.38) | KLK7MEN1KMT2ANPC1KLK5 | |
| SCHEMBL31759044 | 0.85 | ALDH1A1 (0.38) | MEN1KMT2AHCRTR2LMNAALDH1A1 | |
| SCHEMBL29889644 | 0.84 | GPR119 (0.40) | KLK7MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL22555052 | 0.84 | GPR119 (0.40) | KLK7MEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL29889647 | 0.83 | GPR119 (0.40) | KLK7MEN1KMT2ANPC1LMNA | |
| SCHEMBL29889630 | 0.83 | KMT2A (0.36) | KMT2ANPC1ALDH1A1NPSR1RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551577-A1 | FUSED RING KRAS INHIBITORS FOR TREATING DISEASE | Blossomhill Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| CN-119790058-A | Fused cyclic KRAS inhibitors for the treatment of diseases | 荣山医药股份有限公司 | 2025-04-08 | — | — | CN | disclosed |
| WO-2024015262-A1 | FUSED RING KRAS INHIBITORS FOR TREATING DISEASE | BLOSSOMHILL THERAPEUTICS, INC. (US) | 2024-01-18 | — | — | WO | disclosed |