Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3074344 | 1.00 | CYP2D6 (0.38) | CYP2D6SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL3074348 | 1.00 | CYP2D6 (0.38) | CYP2D6SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL9375970 | 0.84 | CYP2D6 (0.35) | CYP2D6SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL4189116 | 0.84 | CYP2D6 (0.35) | CYP2D6SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL3088031 | 0.82 | MEN1 (0.41) | CYP2D6SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL5963643 | 0.82 | KMT2A (0.36) | CYP2D6SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL6332675 | 0.82 | MEN1 (0.41) | CYP2D6SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL3088036 | 0.82 | MEN1 (0.41) | CYP2D6SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL3088041 | 0.82 | MEN1 (0.41) | CYP2D6SMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL2112154 | 0.75 | POLB (0.46) | CYP2D6SMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-7667055-B2 | Processes for the production of polycyclic fused ring compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| US-7667055-B2 | Processes for the production of polycyclic fused ring compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| US-7550608-B2 | Processes for the preparation of docetaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7550608-B2 | Processes for the preparation of docetaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7541458-B2 | β-lactam synthesis | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7541458-B2 | β-lactam synthesis | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| EP-1919926-A2 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | Florida State University Research Foundation, Inc. (US) | 2008-05-14 | — | — | EP | disclosed |
| US-7358378-B2 | Processes for the preparation of paclitaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2008-04-15 | — | — | US | disclosed |
| EP-1888521-A2 | RESOLUTION OF ENANTIOMERIC MIXTURES OF ß-LACTAMS | Florida State University Research Foundation, Inc. (US) | 2008-02-20 | — | — | EP | disclosed |
| WO-2006135692-A2 | PROCESSES FOR THE PREPARATION OF DOCETAXEL | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| WO-2006135656-A2 | PROCESSES FOR THE PREPARATION OF PACLITAXEL | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| WO-2006135655-A2 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| WO-2006135669-A2 | RESOLUTION OF ENANTIOMERIC MIXTURES OF β-LACTAMS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-21 | — | — | WO | disclosed |
| US-20060281934-A1 | Processes for the production of polycyclic fused ring compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281933-A1 | Processes for the preparation of paclitaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281932-A1 | Processes for the preparation of docetaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281918-A1 | Resolution of enantiomeric mixtures of beta-lactams | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281914-A1 | Beta-lactam synthesis | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281934-A1 | Processes for the production of polycyclic fused ring compounds | COASY, PARG, PIN4 | CYP2D6 3387/4885SMN1; SMN2 3512/4885KMT2A 1366/4885 |
| US-20060281918-A1 | Resolution of enantiomeric mixtures of beta-lactams | C9, PEPD, PTMA | CYP2D6 901/4885SMN1; SMN2 2315/4885KMT2A 4369/4885 |
| US-20060281933-A1 | Processes for the preparation of paclitaxel | PDCD10, PDS5B, CASP10 | CYP2D6 283/4885SMN1; SMN2 1025/4885KMT2A 3213/4885 |
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | COASY, PARG, PIN4 | CYP2D6 3387/4885SMN1; SMN2 3512/4885KMT2A 1366/4885 |
| US-20060281914-A1 | Beta-lactam synthesis | COASY, MANBA, DCXR | CYP2D6 1438/4885SMN1; SMN2 2812/4885KMT2A 1934/4885 |
| US-20060281932-A1 | Processes for the preparation of docetaxel | PDCD10, PDS5B, DHCR7 | CYP2D6 243/4885SMN1; SMN2 2381/4885KMT2A 3310/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.