Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6332675 | 1.00 | MEN1 (0.41) | MEN1KMT2ALMNAPTGS2ADORA3 | |
| SCHEMBL3088031 | 1.00 | MEN1 (0.41) | MEN1KMT2ALMNAPTGS2ADORA3 | |
| SCHEMBL3088036 | 1.00 | MEN1 (0.41) | MEN1KMT2ALMNAPTGS2ADORA3 | |
| SCHEMBL3074348 | 0.82 | CYP2D6 (0.38) | MEN1KMT2ALMNAPTGS2CYP2D6 | |
| SCHEMBL3074342 | 0.82 | CYP2D6 (0.38) | MEN1KMT2ALMNAPTGS2CYP2D6 | |
| SCHEMBL3074344 | 0.82 | CYP2D6 (0.38) | MEN1KMT2ALMNAPTGS2CYP2D6 | |
| SCHEMBL5963643 | 0.78 | KMT2A (0.36) | MEN1KMT2ALMNAPTGS2CYP2D6 | |
| SCHEMBL4189116 | 0.77 | CYP2D6 (0.35) | MEN1KMT2ALMNAPTGS2CYP2D6 | |
| SCHEMBL9375970 | 0.77 | CYP2D6 (0.35) | MEN1KMT2ALMNAPTGS2CYP2D6 | |
| SCHEMBL7462796 | 0.77 | ALDH1A1 (0.42) | KMT2ALMNATDP1SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-09-09 | — | — | US | disclosed |
| US-7667055-B2 | Processes for the production of polycyclic fused ring compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2010-02-23 | — | — | US | disclosed |
| US-7550608-B2 | Processes for the preparation of docetaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-23 | — | — | US | disclosed |
| US-7541458-B2 | β-lactam synthesis | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-06-02 | — | — | US | disclosed |
| US-7358378-B2 | Processes for the preparation of paclitaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2008-04-15 | — | — | US | disclosed |
| US-20060281934-A1 | Processes for the production of polycyclic fused ring compounds | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281932-A1 | Processes for the preparation of docetaxel | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
| US-20060281914-A1 | Beta-lactam synthesis | FLORIDA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2006-12-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060281934-A1 | Processes for the production of polycyclic fused ring compounds | COASY, PARG, PIN4 | MEN1 179/4885KMT2A 1366/4885LMNA 978/4885 |
| US-20100228038-A1 | PROCESSES FOR THE PRODUCTION OF POLYCYCLIC FUSED RING COMPOUNDS | COASY, PARG, PIN4 | MEN1 179/4885KMT2A 1366/4885LMNA 978/4885 |
| US-20060281914-A1 | Beta-lactam synthesis | COASY, MANBA, DCXR | MEN1 100/4885KMT2A 1934/4885LMNA 783/4885 |
| US-20060281932-A1 | Processes for the preparation of docetaxel | PDCD10, PDS5B, DHCR7 | MEN1 1927/4885KMT2A 3310/4885LMNA 1589/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.