Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STK39 | Q9UEW8 | 1/20 | 0.57 |
| ▸ | DHODH | Q02127 | 1/20 | 0.53 |
| ▸ | PGR | P06401 | 1/20 | 0.52 |
| ▸ | AR | P10275 | 1/20 | 0.52 |
| ▸ | GCK | P35557 | 1/20 | 0.49 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | TEK | Q02763 | 1/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.46 |
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | TPX2 | Q9ULW0 | 2/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 3/20 | 0.45 |
| ▸ | PARG | Q86W56 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RAF1 | P04049 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21295557 | 1.00 | STK39 (0.57) | STK39DHODHPGRARGCK | |
| SCHEMBL21305446 | 0.93 | STK39 (0.60) | STK39DHODHPGRARIDH1 | |
| SCHEMBL30744028 | 0.93 | STK39 (0.60) | STK39DHODHPGRARIDH1 | |
| SCHEMBL21295431 | 0.90 | STK39 (0.58) | STK39DHODHPGRARIDH1 | |
| SCHEMBL21295412 | 0.88 | STK39 (0.62) | STK39DHODHPGRARAURKB | |
| SCHEMBL21295331 | 0.87 | STK39 (0.56) | STK39DHODHPGRARIDH1 | |
| SCHEMBL11839041 | 0.86 | ALDH1A1 (0.58) | STK39PGRARKDRPNLIP | |
| SCHEMBL23051396 | 0.85 | KMT2A (0.58) | STK39DHODHPGRARIDH1 | |
| SCHEMBL21295337 | 0.85 | STK39 (0.54) | STK39DHODHPGRARIDH1 | |
| SCHEMBL30744002 | 0.85 | STK39 (0.54) | STK39DHODHPGRARIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111819172-B | Triazine derivatives for the treatment of neurotrophin related diseases | 阿泽克制药公司 | 2024-02-06 | — | — | CN | disclosed |