Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC1 | P33527 | 2/20 | 0.57 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.57 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.56 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | CYP1A1 | P04798 | 6/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.54 |
| ▸ | CSNK2A2 | P19784 | 3/20 | 0.53 |
| ▸ | CSNK2B | P67870 | 3/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 3/20 | 0.53 |
| ▸ | TERT | O14746 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21801140 | 1.00 | ABCC1 (0.57) | ABCC1ABCG2CYP1B1ABCB1CYP1A1 | |
| SCHEMBL21801245 | 0.89 | ABCB1 (0.58) | ABCC1ABCG2CYP1B1ABCB1CYP1A1 | |
| SCHEMBL30744133 | 0.89 | ABCB1 (0.58) | ABCC1ABCG2CYP1B1ABCB1CYP1A1 | |
| SCHEMBL21886510 | 0.87 | ABCC1 (0.47) | ABCC1ABCG2CYP1B1ABCB1CYP1A1 | |
| SCHEMBL22230879 | 0.86 | TERT (0.69) | ABCC1ABCG2CYP1B1ABCB1CYP1A1 | |
| SCHEMBL21865645 | 0.84 | CYP1B1 (0.46) | ABCC1ABCG2CYP1B1ABCB1CYP1A1 | |
| SCHEMBL22230875 | 0.83 | CSNK2A2 (0.53) | ABCC1ABCG2CYP1B1ABCB1CYP1A1 | |
| SCHEMBL21801111 | 0.81 | CYP1B1 (0.54) | CYP1B1CYP1A1CYP1A2CSNK2A2CSNK2B | |
| SCHEMBL30744127 | 0.81 | CYP1B1 (0.54) | CYP1B1CYP1A1CYP1A2CSNK2A2CSNK2B | |
| SCHEMBL21801178 | 0.81 | CYP1A1 (0.67) | ABCC1ABCG2CYP1B1ABCB1CYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112601743-B | Flavone compounds for the treatment and prevention of hepatitis b virus diseases | 豪夫迈·罗氏有限公司 | 2023-12-19 | — | — | CN | disclosed |