Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.44 |
| ▸ | CTRC | Q99895 | 1/20 | 0.42 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28110794 | 0.99 | ALDH1A1 (0.46) | CETPALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL25177942 | 0.89 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL7438640 | 0.89 | ALDH1A1 (0.49) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL11571244 | 0.85 | CTRC (0.45) | CETPALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL20794168 | 0.84 | ALDH1A1 (0.49) | CETPALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL7453248 | 0.84 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL15564386 | 0.84 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL18980750 | 0.84 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL28164138 | 0.84 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1LMNAPOLBHSD17B10 | |
| SCHEMBL28110810 | 0.83 | MAPT (0.44) | ALDH1A1L3MBTL1CCR6PAX8SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112218865-B | Pteridinone compounds and uses thereof | 沃泰克斯药物股份有限公司 | 2024-03-12 | — | — | CN | disclosed |