Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MBOAT4 | Q96T53 | 1/20 | 0.42 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.41 |
| ▸ | CTSS | P25774 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | SIRT3 | Q9NTG7 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28814193 | 0.89 | SIRT2 (0.40) | MAPTPAX8CCR6CTSLCTSS | |
| SCHEMBL28110794 | 0.84 | ALDH1A1 (0.46) | L3MBTL1PAX8CCR6CTSLCTSS | |
| SCHEMBL30744367 | 0.83 | CETP (0.46) | L3MBTL1PAX8CCR6SIRT2ALDH1A1 | |
| SCHEMBL20794168 | 0.77 | ALDH1A1 (0.49) | L3MBTL1PAX8CCR6CTSLCTSS | |
| SCHEMBL9306416 | 0.76 | ALDH1A1 (0.43) | L3MBTL1PAX8CCR6SIRT2ALDH1A1 | |
| SCHEMBL27975610 | 0.76 | FKBP1A (0.49) | ALDH1A1 | |
| SCHEMBL25177942 | 0.75 | ALDH1A1 (0.49) | MAPTL3MBTL1PAX8CCR6ALDH1A1 | |
| SCHEMBL7438640 | 0.75 | ALDH1A1 (0.49) | MAPTL3MBTL1PAX8CCR6ALDH1A1 | |
| SCHEMBL11571244 | 0.74 | CTRC (0.45) | L3MBTL1SIRT2ALDH1A1SIRT1SIRT3 | |
| SCHEMBL19546675 | 0.73 | CETP (0.41) | L3MBTL1MBOAT4PAX8CCR6SIRT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104004052-B | Azepine polypeptide compounds and preparation method thereof | 上海交通大学 | 2016-11-23 | — | — | CN | disclosed |
| CN-104004052-A | Azapolypeptide compound and preparation method thereof | UNIV SHANGHAI JIAOTONG | 2014-08-27 | — | — | CN | disclosed |