Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.62 |
| ▸ | KDM4A | O75164 | 2/20 | 0.62 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.62 |
| ▸ | KDM6B | O15054 | 1/20 | 0.62 |
| ▸ | KDM6A | O15550 | 1/20 | 0.62 |
| ▸ | TET3 | O43151 | 1/20 | 0.62 |
| ▸ | KDM4B | O94953 | 1/20 | 0.62 |
| ▸ | KDM5C | P41229 | 1/20 | 0.62 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.62 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.62 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.62 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.62 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.62 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.62 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.62 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | HIF1AN | Q9NWT6 | 1/20 | 0.50 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26550868 | 0.88 | KDM4E (0.62) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL5761189 | 0.88 | L3MBTL1 (0.62) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL69673 | 0.81 | KDM4E (0.77) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL3901228 | 0.79 | KDM4E (0.68) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL4033083 | 0.79 | KDM4E (0.68) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL15703127 | 0.79 | KDM4E (0.68) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL3712212 | 0.78 | NR1H2 (0.49) | KDM4EL3MBTL1RAB9ASLC40A1NR1H2 | |
| SCHEMBL31522858 | 0.77 | ASPH (0.46) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL27947200 | 0.77 | RPS6KB1 (0.58) | KDM4EL3MBTL1KDM4AEGLN1KDM6B | |
| SCHEMBL6068195 | 0.77 | KDM4E (1.00) | KDM4EL3MBTL1KDM4AEGLN1KDM6B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |