Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | CRHR1 | P34998 | 3/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | P2RY14 | Q15391 | 3/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | EED | O75530 | 1/20 | 0.35 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.35 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.35 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.35 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.35 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24906260 | 0.92 | LMNA (0.51) | LMNANOTUMCRHR1ALDH1A1KDM4C | |
| SCHEMBL30744746 | 0.86 | MAPK1 (0.37) | LMNANOTUMCRHR1PTGDR2ALDH1A1 | |
| SCHEMBL21806953 | 0.81 | LMNA (0.39) | LMNANOTUMALDH1A1P2RY14MAPT | |
| SCHEMBL30744742 | 0.81 | HDAC1 (0.39) | LMNANOTUMCRHR1ALDH1A1L3MBTL1 | |
| SCHEMBL6494029 | 0.78 | NPC1 (0.46) | LMNAALDH1A1L3MBTL1MAPK1POLB | |
| SCHEMBL18256013 | 0.75 | CRHR1 (0.46) | LMNANOTUMCRHR1ALDH1A1L3MBTL1 | |
| SCHEMBL24906225 | 0.74 | LMNA (0.45) | LMNAALDH1A1KDM4CP2RY14PTGS2 | |
| SCHEMBL24758136 | 0.74 | LMNA (0.45) | LMNAALDH1A1KDM4CP2RY14PTGS2 | |
| SCHEMBL24757280 | 0.73 | LMNA (0.44) | LMNAPTGDR2ALDH1A1KDM4CP2RY14 | |
| SCHEMBL23273712 | 0.73 | HTT (0.44) | LMNAALDH1A1L3MBTL1MAPTEED |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |