Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | EED | O75530 | 1/20 | 0.33 |
| ▸ | RBBP4 | Q09028 | 1/20 | 0.33 |
| ▸ | SUZ12 | Q15022 | 1/20 | 0.33 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.33 |
| ▸ | AEBP2 | Q6ZN18 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.32 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744771 | 0.86 | LMNA (0.42) | MAPK1LMNAEEDRBBP4SUZ12 | |
| SCHEMBL24906260 | 0.82 | LMNA (0.51) | LMNAALDH1A1PTGER4HTTCRHR1 | |
| SCHEMBL38653859 | 0.75 | ALDH1A1 (0.33) | MAPK1ALDH1A1 | |
| SCHEMBL6494029 | 0.74 | NPC1 (0.46) | MAPK1LMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL24103071 | 0.71 | MAPK1 (0.37) | MAPK1ALDH1A1BRD4CREBBPPTGER4 | |
| SCHEMBL23273712 | 0.70 | HTT (0.44) | LMNAEEDRBBP4SUZ12EZH2 | |
| SCHEMBL23068947 | 0.69 | P2RX7 (0.40) | MAPK1LMNAALDH1A1HTTPDE10A | |
| SCHEMBL6379827 | 0.69 | GRIA1 (0.36) | LMNAHTTGRIA1GRIA2GRIA3 | |
| SCHEMBL16985255 | 0.69 | LMNA (0.35) | MAPK1LMNAEEDRBBP4SUZ12 | |
| SCHEMBL28187731 | 0.69 | MAPK1 (0.32) | MAPK1LMNAEEDRBBP4SUZ12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |