Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.57 |
| ▸ | KDM4A | O75164 | 3/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.57 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.57 |
| ▸ | KDM6B | O15054 | 1/20 | 0.57 |
| ▸ | KDM6A | O15550 | 1/20 | 0.57 |
| ▸ | TET3 | O43151 | 1/20 | 0.57 |
| ▸ | KDM4B | O94953 | 1/20 | 0.57 |
| ▸ | KDM5C | P41229 | 1/20 | 0.57 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.57 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.57 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.57 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.57 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.57 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.57 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.57 |
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744882 | 0.88 | KDM4E (0.61) | KDM4EKDM4AL3MBTL1EGLN1KDM6B | |
| SCHEMBL30744915 | 0.84 | KDM4E (0.57) | KDM4EKDM4AL3MBTL1EGLN1KDM6B | |
| SCHEMBL30744996 | 0.82 | USP2 (0.53) | KDM4EKDM4AL3MBTL1KDM4CPKM | |
| SCHEMBL7324851 | 0.81 | RPS6KB1 (0.59) | KDM4ESLC40A1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL27623408 | 0.79 | CTSB (0.54) | KDM4EPKMRAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7326781 | 0.75 | USP2 (0.53) | KDM4EL3MBTL1SLC40A1PKMALDH1A1 | |
| SCHEMBL69673 | 0.75 | KDM4E (0.77) | KDM4EKDM4AL3MBTL1EGLN1KDM6B | |
| SCHEMBL5480998 | 0.75 | POLB (0.62) | KDM4EL3MBTL1ALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL29574622 | 0.75 | KMT2A (0.65) | KDM4EL3MBTL1PKMALDH1A1SMN1; SMN2 | |
| SCHEMBL353809 | 0.75 | KMT2A (0.65) | KDM4EL3MBTL1PKMALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |