Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | RECQL | P46063 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.47 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30744996 | 0.91 | USP2 (0.53) | USP2MAPK1TP53RECQLHSD17B10 | |
| SCHEMBL7324851 | 0.81 | RPS6KB1 (0.59) | SLC40A1ALDH1A1KDM4E | |
| SCHEMBL18120523 | 0.80 | MAPK1 (0.53) | USP2MAPK1TP53RECQLHSD17B10 | |
| SCHEMBL18394828 | 0.79 | USP2 (0.58) | USP2MAPK1TP53RECQLHSD17B10 | |
| SCHEMBL18395687 | 0.79 | L3MBTL1 (0.57) | USP2MAPK1TP53RECQLHSD17B10 | |
| SCHEMBL13219649 | 0.77 | HTT (0.51) | SMN1; SMN2ALDH1A1KDM4EHTT | |
| SCHEMBL15161250 | 0.77 | SLC40A1 (0.55) | USP2RECQLGAAMAPTPIK3CA | |
| SCHEMBL6609202 | 0.76 | GAA (0.59) | TP53RECQLHSD17B10POLBGAA | |
| SCHEMBL30744816 | 0.75 | KDM4E (0.57) | MAPK1POLBGAAMAPTPIK3CA | |
| SCHEMBL31467097 | 0.74 | ELANE (0.49) | TP53MAPTL3MBTL1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4933447-A | FOR TREATMENT OF CARDIOVASCULAR DISORDERS | SS PHARMACEUTICAL CO., LTD. (JP) | 1990-06-12 | — | — | US | claimed |
| US-4933447-A | FOR TREATMENT OF CARDIOVASCULAR DISORDERS | SS PHARMACEUTICAL CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |
| EP-0308897-A1 | Quinoline derivatives | SS PHARMACEUTICAL CO., LTD. (JP) | 1989-03-29 | — | — | EP | disclosed |