Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | RBP4 | P02753 | 8/20 | 0.41 |
| ▸ | TTR | P02766 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20515876 | 0.88 | ALOX15 (0.61) | ALOX15RBP4TTRALDH1A1HPGD | |
| SCHEMBL30438176 | 0.88 | ALOX15 (0.61) | ALOX15RBP4TTRALDH1A1HPGD | |
| SCHEMBL30421104 | 0.80 | ALOX15 (0.61) | ALOX15GRM5NR1H4TTRALDH1A1 | |
| SCHEMBL18528819 | 0.78 | ALOX15 (0.70) | ALOX15ALDH1A1HPGDHSD17B10P2RY12 | |
| SCHEMBL31389285 | 0.78 | ALOX15 (0.70) | ALOX15ALDH1A1HPGDHSD17B10P2RY12 | |
| SCHEMBL9378807 | 0.78 | ALOX15 (0.66) | ALOX15ALDH1A1HPGDHSD17B10P2RY12 | |
| SCHEMBL2908552 | 0.77 | ALOX15 (0.64) | ALOX15 | |
| SCHEMBL30438115 | 0.77 | ALOX15 (0.64) | ALOX15ALDH1A1HPGDHSD17B10P2RY12 | |
| SCHEMBL31389237 | 0.77 | ALOX15 (0.64) | ALOX15 | |
| SCHEMBL9384536 | 0.76 | ALOX15 (0.62) | ALOX15ALDH1A1HPGDHSD17B10P2RY12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |