Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | NCF1 | P14598 | 4/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 4/20 | 0.45 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | ACP1 | P24666 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385188 | 0.93 | ALOX15 (0.61) | ALOX15NCF1LTB4RP2RY12 | |
| SCHEMBL30438115 | 0.87 | ALOX15 (0.64) | ALOX15NCF1LTB4RP2RY12ALDH1A1 | |
| SCHEMBL9378807 | 0.85 | ALOX15 (0.66) | ALOX15P2RY12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL31389295 | 0.84 | ALOX15 (0.61) | ALOX15NCF1P2RY12ALDH1A1HPGD | |
| SCHEMBL30438659 | 0.84 | ALOX15 (0.69) | ALOX15NCF1P2RY12ALDH1A1HPGD | |
| SCHEMBL20515870 | 0.84 | ALOX15 (0.69) | ALOX15NCF1P2RY12ALDH1A1HPGD | |
| SCHEMBL31389263 | 0.83 | ALOX15 (0.59) | ALOX15NCF1ALDH1A1HPGD | |
| SCHEMBL18528819 | 0.82 | ALOX15 (0.70) | ALOX15LMNANCF1P2RY12ALDH1A1 | |
| SCHEMBL31389285 | 0.82 | ALOX15 (0.70) | ALOX15LMNANCF1P2RY12ALDH1A1 | |
| SCHEMBL10678548 | 0.82 | ACP1 (0.57) | LMNALTB4RHPGDACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5026700-A | Certain quinolines and thienopyridines as excitatory amino acid antagonists | MERRELL DOW PHARMACEUTICALS (US) | 1991-06-25 | — | — | US | claimed |
| EP-0398283-B1 | Excitatory amino acid antagonists | MERRELL DOW PHARMA (US) | 1994-11-02 | — | — | EP | disclosed |
| US-5112821-A | Excitatory amino acid antagonists which are certain thienopyridives | MERRELL DOW PHARMACEUTICALS INC. (US) | 1992-05-12 | — | — | US | disclosed |
| US-5026700-A | Certain quinolines and thienopyridines as excitatory amino acid antagonists | MERRELL DOW PHARMACEUTICALS (US) | 1991-06-25 | — | — | US | disclosed |
| EP-0398283-A1 | Excitatory amino acid antagonists | MERRELL DOW PHARMACEUTICALS INC. (US) | 1990-11-22 | — | — | EP | disclosed |