Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.70 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | NCF1 | P14598 | 1/20 | 0.48 |
| ▸ | GUSB | P08236 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18528819 | 1.00 | ALOX15 (0.70) | ALOX15P2RY12KDM4ELMNASMN1; SMN2 | |
| SCHEMBL31389238 | 0.87 | ALOX15 (0.57) | ALOX15P2RY12KDM4ELMNASMN1; SMN2 | |
| SCHEMBL9378807 | 0.85 | ALOX15 (0.66) | ALOX15P2RY12KDM4ESMN1; SMN2ALDH1A1 | |
| SCHEMBL30744749 | 0.84 | ALOX15 (0.65) | ALOX15P2RY12ALDH1A1HPGDHSD17B10 | |
| SCHEMBL20515870 | 0.84 | ALOX15 (0.69) | ALOX15P2RY12KDM4EALDH1A1HPGD | |
| SCHEMBL30438659 | 0.84 | ALOX15 (0.69) | ALOX15P2RY12KDM4EALDH1A1HPGD | |
| SCHEMBL2908552 | 0.84 | ALOX15 (0.64) | ALOX15SMN1; SMN2 | |
| SCHEMBL31389237 | 0.84 | ALOX15 (0.64) | ALOX15SMN1; SMN2 | |
| SCHEMBL30438115 | 0.84 | ALOX15 (0.64) | ALOX15P2RY12ALDH1A1HPGDNCF1 | |
| SCHEMBL19579748 | 0.83 | ALOX15 (0.49) | ALOX15P2RY12LMNASMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119264047-A | Quinoline derivative histone deacetylase inhibitor and preparation method and application thereof | 山东大学 | 2025-01-07 | — | — | CN | disclosed |