Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.50 |
| ▸ | AURKA | O14965 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | PRNP | P04156 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.40 |
| ▸ | IGFBP3 | P17936 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6080102 | 0.83 | KDM4E (0.56) | KDM4ETDP1MAPTRAB9AALDH1A1 | |
| SCHEMBL3333164 | 0.83 | GRM2 (0.48) | KDM4ETDP1MAPTRAB9AGRM2 | |
| SCHEMBL13977964 | 0.83 | AURKA (0.59) | KDM4ETDP1RAB9AGRM2AURKA | |
| SCHEMBL28913989 | 0.81 | CYP1A2 (0.53) | KDM4EMAPTRAB9AGRM2ALDH1A1 | |
| SCHEMBL13857985 | 0.81 | AURKA (0.51) | KDM4ETDP1GRM2AURKAGPR35 | |
| SCHEMBL8114876 | 0.81 | GPR35 (0.54) | KDM4ETDP1MAPTGRM2AURKA | |
| SCHEMBL30421043 | 0.81 | ALOX15 (0.62) | KDM4ERAB9AGRM2AURKAALDH1A1 | |
| SCHEMBL14919681 | 0.80 | GRM2 (0.78) | GRM2AURKAIGFBP3 | |
| SCHEMBL30744928 | 0.80 | GRM2 (0.43) | KDM4EGRM2AURKAALOX15ADORA2A | |
| SCHEMBL6596151 | 0.79 | GPR35 (0.56) | KDM4ETDP1MAPTRAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | claimed |
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |