Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20944381 | 1.00 | KDM4E (0.50) | KDM4EALDH1A1GAAGPR35CYP1A2 | |
| SCHEMBL20944231 | 0.85 | LMNA (0.47) | KDM4EALDH1A1GAAGPR35HPGD | |
| SCHEMBL20944473 | 0.83 | HCRTR1 (0.44) | KDM4EALDH1A1GAAHPGD | |
| SCHEMBL20944584 | 0.81 | HCRTR1 (0.40) | KDM4EALDH1A1GAAHPGDMAPK1 | |
| SCHEMBL20944049 | 0.81 | MAPT (0.39) | KDM4EALDH1A1CYP1A2HPGDLMNA | |
| SCHEMBL20944290 | 0.78 | NQO2 (0.39) | KDM4EALDH1A1GAAGPR35HPGD | |
| SCHEMBL30745067 | 0.78 | NQO2 (0.39) | KDM4EALDH1A1GAAGPR35HPGD | |
| SCHEMBL20944312 | 0.77 | MAPT (0.39) | KDM4EALDH1A1GAAGPR35CYP1A2 | |
| SCHEMBL30744980 | 0.77 | MAPT (0.39) | KDM4EALDH1A1GAAGPR35CYP1A2 | |
| SCHEMBL13593209 | 0.77 | ALDH1A1 (0.46) | KDM4EALDH1A1GAACYP1A2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |