Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3109659 | 0.91 | MAPT (0.49) | MAPTMEN1KMT2AHSP90AA1SMN1; SMN2 | |
| SCHEMBL30688568 | 0.88 | MAPT (0.55) | MAPTKMT2ATDP1KDM4EALDH1A1 | |
| SCHEMBL30744991 | 0.83 | LMNA (0.48) | MAPTMEN1KMT2AHSP90AA1SMN1; SMN2 | |
| SCHEMBL30745029 | 0.82 | MAPT (0.44) | MAPTMEN1KMT2AHSP90AA1SMN1; SMN2 | |
| SCHEMBL30745004 | 0.82 | MEN1 (0.43) | MAPTMEN1KMT2AHSP90AA1SMN1; SMN2 | |
| SCHEMBL6822680 | 0.81 | KDM4E (0.55) | MAPTMEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL30572435 | 0.80 | KDM4E (0.57) | MAPTMEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL27791366 | 0.77 | MAPT (0.48) | MAPTSMN1; SMN2TDP1KDM4EALDH1A1 | |
| SCHEMBL30745017 | 0.77 | MAPT (0.40) | MAPTMEN1KMT2AHSP90AA1SMN1; SMN2 | |
| SCHEMBL23866770 | 0.77 | CYP19A1 (0.44) | MEN1KMT2AHSP90AA1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |