Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.40 |
| ▸ | GABRP | O00591 | 2/20 | 0.40 |
| ▸ | GABRD | O14764 | 2/20 | 0.40 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.40 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.40 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.40 |
| ▸ | GABRE | P78334 | 2/20 | 0.40 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.40 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.40 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.40 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745053 | 0.84 | KDM4E (0.44) | MAPTMEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL30745029 | 0.80 | MAPT (0.44) | MAPTMEN1HSP90AA1KMT2AGABRA1 | |
| SCHEMBL30745004 | 0.78 | MEN1 (0.43) | MAPTMEN1HSP90AA1KMT2AGABRA1 | |
| SCHEMBL30745009 | 0.77 | MAPT (0.47) | MAPTMEN1HSP90AA1KMT2AGABRA1 | |
| SCHEMBL30744991 | 0.77 | LMNA (0.48) | MAPTMEN1HSP90AA1KMT2AGABRA1 | |
| SCHEMBL30688569 | 0.76 | HRH4 (0.53) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL3109659 | 0.75 | MAPT (0.49) | MAPTMEN1HSP90AA1KMT2AALDH1A1 | |
| SCHEMBL20944158 | 0.73 | GABRA1 (0.52) | MAPTMEN1HSP90AA1KMT2AGABRA1 | |
| SCHEMBL753481 | 0.70 | POLB (0.51) | MAPTMEN1KMT2AALDH1A1HPGD | |
| SCHEMBL31394801 | 0.69 | LMNA (0.44) | ALDH1A1HPGDSMN1; SMN2USP2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |