Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30745029 | 0.85 | MAPT (0.44) | MEN1KMT2AKDM4EHSP90AA1SMN1; SMN2 | |
| SCHEMBL30745009 | 0.82 | MAPT (0.47) | MEN1KMT2AKDM4EHSP90AA1SMN1; SMN2 | |
| SCHEMBL3109659 | 0.80 | MAPT (0.49) | MEN1KMT2AKDM4EHSP90AA1SMN1; SMN2 | |
| SCHEMBL30744991 | 0.79 | LMNA (0.48) | MEN1KMT2AL3MBTL1HSP90AA1SMN1; SMN2 | |
| SCHEMBL30745017 | 0.78 | MAPT (0.40) | MEN1KMT2AHSP90AA1SMN1; SMN2MAPT | |
| SCHEMBL13465546 | 0.75 | OGFRL1 (0.46) | MEN1KMT2AKDM4EL3MBTL1SMN1; SMN2 | |
| SCHEMBL4147275 | 0.73 | LMNA (0.48) | MEN1KMT2AKDM4EL3MBTL1HSP90AA1 | |
| SCHEMBL2510778 | 0.73 | ADORA3 (0.44) | MEN1KMT2AKDM4ESMN1; SMN2ADORA3 | |
| SCHEMBL31440811 | 0.73 | MAPT (0.56) | MEN1KMT2AKDM4EHSP90AA1SMN1; SMN2 | |
| SCHEMBL26615792 | 0.73 | MAPT (0.56) | MEN1KMT2AKDM4EHSP90AA1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |