Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | PPARG | P37231 | 2/20 | 0.52 |
| ▸ | PPARD | Q03181 | 1/20 | 0.52 |
| ▸ | PPARA | Q07869 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 3/20 | 0.50 |
| ▸ | NMT1 | P30419 | 4/20 | 0.49 |
| ▸ | NMT2 | O60551 | 1/20 | 0.49 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.47 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.47 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.47 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.47 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20944218 | 0.81 | MEN1 (0.57) | MEN1HSP90AA1KMT2APPARGPPARD | |
| SCHEMBL30745018 | 0.81 | MAOA (0.44) | MEN1HSP90AA1KMT2AMAOBALDH1A1 | |
| SCHEMBL4847906 | 0.76 | PTPN1 (0.63) | PPARGPPARDMAOBALDH1A1PTPN1 | |
| SCHEMBL8629057 | 0.75 | MEN1 (0.52) | MEN1HSP90AA1KMT2APPARGPPARD | |
| SCHEMBL8628372 | 0.75 | MEN1 (0.52) | MEN1HSP90AA1KMT2APPARGPPARD | |
| SCHEMBL8627840 | 0.75 | KMT2A (0.52) | MEN1HSP90AA1KMT2APPARGPPARD | |
| SCHEMBL4363943 | 0.74 | MAOB (0.57) | MEN1KMT2AMAOBALDH1A1HPGD | |
| SCHEMBL8000403 | 0.74 | MAOB (0.57) | MEN1KMT2AMAOBALDH1A1PTPN1 | |
| SCHEMBL8629713 | 0.74 | KMT2A (0.53) | MEN1HSP90AA1KMT2APPARGPPARD | |
| SCHEMBL8629309 | 0.74 | MEN1 (0.53) | MEN1HSP90AA1KMT2APPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111295382-B | Bridged bicyclic compounds as farnesyl ester X receptor modulators | 百时美施贵宝公司 | 2024-02-02 | — | — | CN | disclosed |